Bergenin Activates SIRT1 as a Novel Therapeutic Agent for Osteogenesis of Bone Mesenchymal Stem Cells

Bone mesenchymal stem cells (BMSCs) are important candidates for bone regeneration. The role of Bergenin, a C-glucoside of 4-O-methyl gallic acid obtained from the species, Bergenia, in BMSC osteogenesis has not yet been elucidated. We therefore investigated the effects of Bergenin on the osteogenes...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Hou, Weiduo, Ye, Chenyi, Chen, Mo, Li, Weixu, Gao, Xiang, He, Rongxin, Zheng, Qiang, Zhang, Wei
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586741/
https://ncbi.nlm.nih.gov/pubmed/31258473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00618
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