Human Umbilical Tissue-Derived Cells Secrete Soluble VEGFR1 and Inhibit Choroidal Neovascularization

Exudative age-related macular degeneration (AMD), characterized by choroidal neovascularization (CNV), is the leading cause of irreversible blindness in developed countries. Anti-vascular endothelial growth factor (VEGF) drugs are the standard treatment for AMD, but they have limitations. Cell thera...

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Vydáno v:Mol Ther Methods Clin Dev
Hlavní autoři: Cao, Jing, Yang, Rong, Smith, Taylor E., Evans, Stephanie, McCollum, Gary W., Pomerantz, Steven C., Petley, Theodore, Harris, Ian R., Penn, John S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586593/
https://ncbi.nlm.nih.gov/pubmed/31276010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.05.007
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