Atomic resolution map of the soluble amyloid beta assembly toxic surfaces

Soluble amyloid beta assemblies (Aβ(n)) are neurotoxic and play a central role in the early phases of the pathogenesis cascade leading to Alzheimer's disease. However, the current knowledge about the molecular determinants of Aβ(n) toxicity is at best scant. Here, we comparatively analyze Aβ(n)...

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Bibliografski detalji
Izdano u:Chem Sci
Glavni autori: Ahmed, Rashik, Akcan, Michael, Khondker, Adree, Rheinstädter, Maikel C., Bozelli, José C., Epand, Richard M., Huynh, Vincent, Wylie, Ryan G., Boulton, Stephen, Huang, Jinfeng, Verschoor, Chris P., Melacini, Giuseppe
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2019
Teme:
Chemistry
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585597/
https://ncbi.nlm.nih.gov/pubmed/31360412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc01331h
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