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Organocopper cross-coupling reaction for C–C bond formation on highly sterically hindered structures

We describe a powerful, broadly applicable cross-coupling protocol that enables carbon–carbon bond formation at highly sterically hindered carbon centers (both sp(2) and sp(3)) by employing organocopper reagents under palladium catalysis. Experimental studies and theoretical calculations indicated t...

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Détails bibliographiques
Publié dans:Chem Sci
Auteurs principaux: Oi, Miku, Takita, Ryo, Kanazawa, Junichiro, Muranaka, Atsuya, Wang, Chao, Uchiyama, Masanobu
Format: Artigo
Langue:Inglês
Publié: Royal Society of Chemistry 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585593/
https://ncbi.nlm.nih.gov/pubmed/31360416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc00891h
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