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Stereoselective construction of sterically hindered oxaspirocycles via chiral bidentate directing group-mediated C(sp(3))–O bond formation

The systematic investigation of chiral bidentate auxiliaries has resulted in the discovery of a chiral 2,2-dimethyl-1-(pyridin-2-yl)propan-1-amine-derived directing group that enables stereoselective palladium(ii)-catalyzed intramolecular C(sp(3))–O bond formation. This new chiral directing group ex...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Kim, Yechan, Kim, Seoung-Tae, Kang, Dahye, Sohn, Te-ik, Jang, Eunyoung, Baik, Mu-Hyun, Hong, Sungwoo
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875089/
https://ncbi.nlm.nih.gov/pubmed/29629170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc04691j
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