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Identification of kinases and interactors of p53 using kinase-catalyzed crosslinking and immunoprecipitation (K-CLIP)

Kinase enzymes phosphorylate protein substrates in a highly ordered manner to control cell signaling. Unregulated kinase activity is associated with a variety of disease states, most notably cancer, making the characterization of kinase activity in cellulo critical to understand disease formation. H...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Principais autores: Garret, Satish, Gamage, Aparni K., Faner, Todd R., Dedigama-Arachchige, Pavithra, Pflum, Mary Kay H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585437/
https://ncbi.nlm.nih.gov/pubmed/30339384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b10160
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