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Studies on the treatment of melanoma with folate acid conjugated dextran and lauryl alcohol loaded with IMD0354

Background: IMD-0354 is a kind of hydrophobic small molecule inhibitor of IKKβ, which can effectively inhibit the NF-κB pathway. Besides, IMD-0354 can inhibit a variety of tumor cells in culture, but its poor water solubility and low utilization have limited its clinical application. Methods: In thi...

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Podrobná bibliografie
Vydáno v:Onco Targets Ther
Hlavní autoři: Liu, Can, Chen, Wei, Chen, Zizi, Yan, Yu, Wang, Qing, Xie, Huiqing, Chen, Xiang, Wang, Aijun, Tang, Shijie, Zhou, Jianda
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585409/
https://ncbi.nlm.nih.gov/pubmed/31354298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S207685
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