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Genome-wide enhancer annotations differ significantly in genomic distribution, evolution, and function

BACKGROUND: Non-coding gene regulatory enhancers are essential to transcription in mammalian cells. As a result, a large variety of experimental and computational strategies have been developed to identify cis-regulatory enhancer sequences. Given the differences in the biological signals assayed, so...

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Vydáno v:BMC Genomics
Hlavní autoři: Benton, Mary Lauren, Talipineni, Sai Charan, Kostka, Dennis, Capra, John A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585034/
https://ncbi.nlm.nih.gov/pubmed/31221079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5779-x
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