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Role of IDO and TDO in Cancers and Related Diseases and the Therapeutic Implications

Kynurenine (Kyn) pathway is a significant metabolic pathway of tryptophan (Trp). The metabolites of the Kyn pathway are closely correlated with numerous diseases. Two main enzymes, indoleamine-2,3-dioxygenase (IDO) and tryptophan-2,3-dioxygenase (TDO or TDO2), regulate the first and rate-limiting st...

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Bibliografski detalji
Izdano u:J Cancer
Glavni autori: Ye, Zixiang, Yue, Linxiu, Shi, Jiachen, Shao, Mingmei, Wu, Tao
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584917/
https://ncbi.nlm.nih.gov/pubmed/31258785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.31727
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