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Role of IDO and TDO in Cancers and Related Diseases and the Therapeutic Implications
Kynurenine (Kyn) pathway is a significant metabolic pathway of tryptophan (Trp). The metabolites of the Kyn pathway are closely correlated with numerous diseases. Two main enzymes, indoleamine-2,3-dioxygenase (IDO) and tryptophan-2,3-dioxygenase (TDO or TDO2), regulate the first and rate-limiting st...
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| Udgivet i: | J Cancer |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Ivyspring International Publisher
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6584917/ https://ncbi.nlm.nih.gov/pubmed/31258785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.31727 |
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