Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex

Atomic-resolution structure determination is crucial for understanding protein function. Cryo-EM and NMR spectroscopy both provide structural information, but currently cryo-EM does not routinely give access to atomic-level structural data, and, generally, NMR structure determination is restricted t...

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Pubblicato in:Nat Commun
Autori principali: Gauto, Diego F., Estrozi, Leandro F., Schwieters, Charles D., Effantin, Gregory, Macek, Pavel, Sounier, Remy, Sivertsen, Astrid C., Schmidt, Elena, Kerfah, Rime, Mas, Guillaume, Colletier, Jacques-Philippe, Güntert, Peter, Favier, Adrien, Schoehn, Guy, Schanda, Paul, Boisbouvier, Jerome
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584647/
https://ncbi.nlm.nih.gov/pubmed/31217444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10490-9
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