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Sensitive proton-detected solid-state NMR spectroscopy of large proteins with selective CH(3) labelling: application to the 50S ribosome subunit

Solid-state NMR spectroscopy allows the characterization of structure, interactions and dynamics of insoluble and/or very large proteins. Sensitivity and resolution are often major challenges for obtaining atomic-resolution information, in particular for very large protein complexes. Here we show th...

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Bibliografiske detaljer
Udgivet i:Chem Commun (Camb)
Main Authors: Kurauskas, Vilius, Crublet, Elodie, Macek, Pavel, Kerfah, Rime, Gauto, Diego F., Boisbouvier, Jérôme, Schanda, Paul
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958370/
https://ncbi.nlm.nih.gov/pubmed/27385633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc04484k
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