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Energetic, Structural and Dynamic Properties of Nucleobase-Urea Interactions that Aid in Urea Assisted RNA Unfolding

Understanding the structure-function relationships of RNA has become increasingly important given the realization of its functional role in various cellular processes. Chemical denaturation of RNA by urea has been shown to be beneficial in investigating RNA stability and folding. Elucidation of the...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Jaganade, Tanashree, Chattopadhyay, Aditya, Pazhayam, Nila M., Priyakumar, U. Deva
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584539/
https://ncbi.nlm.nih.gov/pubmed/31217494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45010-8
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