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Structure-Activity Relationships of Baicalein and its Analogs as Novel TSLP Inhibitors

Thymic stromal lymphopoietin (TSLP) plays an important role in the differentiation and proliferation of Th2 cells, resulting in eosinophilic inflammation and numerous allergic diseases. Baicalein (1), a major component of Scutellaria baicalensis, was found to be the first small molecule to block TSL...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Park, Bernie Byunghoon, Choi, Jae Wan, Park, Dawon, Choi, Doyoung, Paek, Jiwon, Kim, Hyun Jung, Son, Se-Young, Mushtaq, Ameeq Ul, Shin, Hyeji, Kim, Sang Hoon, Zhou, Yuanyuan, Lim, Taehyeong, Park, Ji Young, Baek, Ji-Young, Kim, Kyul, Kwon, Hongmok, Son, Sang-Hyun, Chung, Ka Young, Jeong, Hyun-Ja, Kim, Hyung-Min, Jung, Yong Woo, Lee, Kiho, Lee, Ki Yong, Byun, Youngjoo, Jeon, Young Ho
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584507/
https://ncbi.nlm.nih.gov/pubmed/31217492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44853-5
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