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Structure-Activity Relationships of Baicalein and its Analogs as Novel TSLP Inhibitors
Thymic stromal lymphopoietin (TSLP) plays an important role in the differentiation and proliferation of Th2 cells, resulting in eosinophilic inflammation and numerous allergic diseases. Baicalein (1), a major component of Scutellaria baicalensis, was found to be the first small molecule to block TSL...
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| Publicat a: | Sci Rep |
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| Autors principals: | , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6584507/ https://ncbi.nlm.nih.gov/pubmed/31217492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44853-5 |
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