Structure-Activity Relationships of Baicalein and its Analogs as Novel TSLP Inhibitors

Thymic stromal lymphopoietin (TSLP) plays an important role in the differentiation and proliferation of Th2 cells, resulting in eosinophilic inflammation and numerous allergic diseases. Baicalein (1), a major component of Scutellaria baicalensis, was found to be the first small molecule to block TSL...

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書誌詳細
出版年:Sci Rep
主要な著者: Park, Bernie Byunghoon, Choi, Jae Wan, Park, Dawon, Choi, Doyoung, Paek, Jiwon, Kim, Hyun Jung, Son, Se-Young, Mushtaq, Ameeq Ul, Shin, Hyeji, Kim, Sang Hoon, Zhou, Yuanyuan, Lim, Taehyeong, Park, Ji Young, Baek, Ji-Young, Kim, Kyul, Kwon, Hongmok, Son, Sang-Hyun, Chung, Ka Young, Jeong, Hyun-Ja, Kim, Hyung-Min, Jung, Yong Woo, Lee, Kiho, Lee, Ki Yong, Byun, Youngjoo, Jeon, Young Ho
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584507/
https://ncbi.nlm.nih.gov/pubmed/31217492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44853-5
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