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N‐acetylcysteine Attenuates Cobalt Nanoparticle‐Induced Cytotoxic Effects through Inhibition of Cell Death, Reactive Oxygen Species‐related Signaling and Cytokines Expression
OBJECTIVE: Complex cobalt‐chromium alloys, bearing surfaces of the second‐generation metal‐on‐metal (MoM) hip prostheses, are subject to wear and generate cobalt nanoparticles (CoNPs). CoNPs could reduce cellular viability, activate the mitogen‐activated protein kinase (MAPK) pathway and increase ce...
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| Publicado no: | Orthop Surg |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons Australia, Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6584440/ https://ncbi.nlm.nih.gov/pubmed/28032714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/os.12298 |
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