N‐acetylcysteine Attenuates Cobalt Nanoparticle‐Induced Cytotoxic Effects through Inhibition of Cell Death, Reactive Oxygen Species‐related Signaling and Cytokines Expression

OBJECTIVE: Complex cobalt‐chromium alloys, bearing surfaces of the second‐generation metal‐on‐metal (MoM) hip prostheses, are subject to wear and generate cobalt nanoparticles (CoNPs). CoNPs could reduce cellular viability, activate the mitogen‐activated protein kinase (MAPK) pathway and increase ce...

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Vydáno v:Orthop Surg
Hlavní autoři: Liu, Ya‐ke, Yang, Hong‐wei, Wang, Meng‐hong, Wang, Wei, Liu, Fan, Yang, Hui‐lin
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons Australia, Ltd 2016
Témata:
Scientific Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584440/
https://ncbi.nlm.nih.gov/pubmed/28032714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/os.12298
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