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Regulatory Molecules and Corresponding Processes of BCR-ABL Protein Degradation
The BCR-ABL fusion protein with strong tyrosine kinase activity is one of the molecular biological bases of leukemia. Imatinib (Gleevec), a specific targeted drug for the treatment of chronic myeloid leukemia (CML), was developed for inhibiting the kinase activity of the BCR-ABL fusion protein. Desp...
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| Publicado no: | J Cancer |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ivyspring International Publisher
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6584333/ https://ncbi.nlm.nih.gov/pubmed/31258755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.29528 |
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