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Regulated Activation of the PAR Polarity Network Ensures a Timely and Specific Response to Spatial Cues

How do cells polarize at the correct time and in response to the correct cues? In the C. elegans zygote, the timing and geometry of polarization rely on a single dominant cue—the sperm centrosome—that matures at the end of meiosis and specifies the nascent posterior. Polarization requires that the c...

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Vydáno v:Curr Biol
Hlavní autoři: Reich, Jacob D., Hubatsch, Lars, Illukkumbura, Rukshala, Peglion, Florent, Bland, Tom, Hirani, Nisha, Goehring, Nathan W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584329/
https://ncbi.nlm.nih.gov/pubmed/31155349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2019.04.058
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