aPKC Cycles between Functionally Distinct PAR Protein Assemblies to Drive Cell Polarity

The conserved polarity effector proteins PAR-3, PAR-6, CDC-42, and atypical protein kinase C (aPKC) form a core unit of the PAR protein network, which plays a central role in polarizing a broad range of animal cell types. To functionally polarize cells, these proteins must activate aPKC within a spa...

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Gepubliceerd in:Dev Cell
Hoofdauteurs: Rodriguez, Josana, Peglion, Florent, Martin, Jack, Hubatsch, Lars, Reich, Jacob, Hirani, Nisha, Gubieda, Alicia G., Roffey, Jon, Fernandes, Artur Ribeiro, St Johnston, Daniel, Ahringer, Julie, Goehring, Nathan W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563072/
https://ncbi.nlm.nih.gov/pubmed/28781174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.07.007
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