Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2

Lsr2 is a nucleoid-associated protein conserved throughout the actinobacteria, including the antibiotic-producing Streptomyces. Streptomyces species encode paralogous Lsr2 proteins (Lsr2 and Lsr2-like, or LsrL), and we show here that of the two, Lsr2 has greater functional significance. We found tha...

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Pubblicato in:eLife
Autori principali: Gehrke, Emma J, Zhang, Xiafei, Pimentel-Elardo, Sheila M, Johnson, Andrew R, Rees, Christiaan A, Jones, Stephanie E, Hindra, Gehrke, Sebastian S, Turvey, Sonya, Boursalie, Suzanne, Hill, Jane E, Carlson, Erin E, Nodwell, Justin R, Elliot, Marie A
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2019
Soggetti:
Microbiology and Infectious Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584129/
https://ncbi.nlm.nih.gov/pubmed/31215866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47691
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