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Synthetic bovine NK-lysin-derived peptide (bNK2A) does not require intra-chain disulfide bonds for bactericidal activity

Bovine NK-lysins are cationic antimicrobial proteins found predominantly in the cytosolic granules of T lymphocytes and NK-cells. NK-lysin-derived peptides show antimicrobial activity against both Gram positive and Gram negative bacteria. Mature NK-lysin protein has six well-conserved cysteine resid...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dassanayake, Rohana P., Falkenberg, Shollie M., Nicholson, Eric M., Briggs, Robert E., Tatum, Fred M., Sharma, Vijay K., Reinhardt, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583974/
https://ncbi.nlm.nih.gov/pubmed/31216348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218507
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