Synthetic bovine NK-lysin-derived peptide (bNK2A) does not require intra-chain disulfide bonds for bactericidal activity

Bovine NK-lysins are cationic antimicrobial proteins found predominantly in the cytosolic granules of T lymphocytes and NK-cells. NK-lysin-derived peptides show antimicrobial activity against both Gram positive and Gram negative bacteria. Mature NK-lysin protein has six well-conserved cysteine resid...

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Veröffentlicht in:PLoS One
Hauptverfasser: Dassanayake, Rohana P., Falkenberg, Shollie M., Nicholson, Eric M., Briggs, Robert E., Tatum, Fred M., Sharma, Vijay K., Reinhardt, Timothy A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583974/
https://ncbi.nlm.nih.gov/pubmed/31216348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218507
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