Pharmacological modulation of b-adrenoceptors as a new cardioprotective strategy for therapy of myocardial dysfunction induced by ischemia and reperfusion

PURPOSE: To evaluate the cardioprotective response of the pharmacological modulation of β-adrenergic receptors (β-AR) in animal model of cardiac ischemia and reperfusion (CIR), in spontaneously hypertensive (SHR) and normotensive (NWR) rats. METHODS: CIR was induced by the occlusion of left anterior...

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Pubblicato in:Acta Cir Bras
Autori principali: Menezes-Rodrigues, Francisco Sandro, Errante, Paolo Ruggero, Tavares, José Gustavo Padrão, Ferraz, Renato Ribeiro Nogueira, Gomes, Walter José, Taha, Murched Omar, Scorza, Carla Alessandra, Scorza, Fúlvio Alexandre, Caricati-Neto, Afonso
Natura: Artigo
Lingua:Inglês
Pubblicazione: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2019
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ORIGINAL ARTICLE
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583939/
https://ncbi.nlm.nih.gov/pubmed/31166461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/s0102-865020190050000005
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