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Denatured-State Energy Landscapes of a Protein Structural Database Reveal the Energetic Determinants of a Framework Model for Folding

Position-specific denatured-state thermodynamics were determined for a database of human proteins by use of an ensemble-based model of protein structure. The results of modeling denatured protein in this manner reveal important sequence-dependent thermodynamic properties in the denatured ensembles a...

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Bibliografiske detaljer
Udgivet i:J Mol Biol
Main Authors: Wang, Suwei, Gu, Jenny, Larson, Scott A., Whitten, Steven T., Hilser, Vincent J.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583914/
https://ncbi.nlm.nih.gov/pubmed/18616947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.06.046
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