Hypo-Osmotic-Like Stress Underlies General Cellular Defects of Aneuploidy

Aneuploidy, referring to unbalanced chromosome numbers, represents a class of genetic variation associated with cancer, birth defects and eukaryotic microbes(1–4). Whereas it is known that each aneuploid chromosome stoichiometry can give rise to a distinct pattern of gene expression and phenotypic p...

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Publicat a:Nature
Autors principals: Tsai, Hung-Ji, Nelliat, Anjali R., Choudhury, Mohammad Ikbal, Kucharavy, Andrei, Bradford, William D., Cook, Malcolm E., Kim, Jisoo, Mair, Devin B., Sun, Sean X., Schatz, Michael C., Li, Rong
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583789/
https://ncbi.nlm.nih.gov/pubmed/31068692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1187-2
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