Chemoresistance in the Human Triple-Negative Breast Cancer Cell Line MDA-MB-231 Induced by Doxorubicin Gradient Is Associated with Epigenetic Alterations in Histone Deacetylase

Chemoresistance is one of the major causes of therapeutic failure in breast cancer patients. In this study, the mechanism of chemoresistance in human triple-negative breast cancer (TNBC) cells (MDA-MB-231) induced by doxorubicin (DOX) gradient was investigated. These DOX-resistant cells showed highe...

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Detalhes bibliográficos
Publicado no:J Oncol
Main Authors: Han, Jeonghun, Lim, Wanyoung, You, Daeun, Jeong, Yisun, Kim, Sangmin, Lee, Jeong Eon, Shin, Tae Hwan, Lee, Gwang, Park, Sungsu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582875/
https://ncbi.nlm.nih.gov/pubmed/31275376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1345026
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