Chemoresistance in the Human Triple-Negative Breast Cancer Cell Line MDA-MB-231 Induced by Doxorubicin Gradient Is Associated with Epigenetic Alterations in Histone Deacetylase

Chemoresistance is one of the major causes of therapeutic failure in breast cancer patients. In this study, the mechanism of chemoresistance in human triple-negative breast cancer (TNBC) cells (MDA-MB-231) induced by doxorubicin (DOX) gradient was investigated. These DOX-resistant cells showed highe...

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Dettagli Bibliografici
Pubblicato in:J Oncol
Autori principali: Han, Jeonghun, Lim, Wanyoung, You, Daeun, Jeong, Yisun, Kim, Sangmin, Lee, Jeong Eon, Shin, Tae Hwan, Lee, Gwang, Park, Sungsu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582875/
https://ncbi.nlm.nih.gov/pubmed/31275376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1345026
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