Development of a novel ssDNA aptamer targeting neutrophil gelatinase-associated lipocalin and its application in clinical trials

BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL) is a promising biomarker of early diagnosis and prediction for acute kidney injury (AKI). However, the current program for NGAL detection is not extensively applied in clinics due to the high expense of antibodies. Nucleic acid aptamers a...

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Bibliografiske detaljer
Udgivet i:	J Transl Med
Main Authors:	Hong, Xiaoqian, Yan, Huihui, Xie, Fuan, Wang, Kaiyu, Wang, Qiang, Huang, Huijuan, Yang, Kunrong, Huang, Suhong, Zhao, Tingting, Wang, Junkai, Chen, Yunyun, Liu, Kuancan, Lan, Xiaopeng
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2019
Fag:	Research
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6582607/ https://ncbi.nlm.nih.gov/pubmed/31215436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1955-7
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Development of a novel ssDNA aptamer targeting neutrophil gelatinase-associated lipocalin and its application in clinical trials

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