Development of a novel ssDNA aptamer targeting neutrophil gelatinase-associated lipocalin and its application in clinical trials

BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL) is a promising biomarker of early diagnosis and prediction for acute kidney injury (AKI). However, the current program for NGAL detection is not extensively applied in clinics due to the high expense of antibodies. Nucleic acid aptamers a...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Hong, Xiaoqian, Yan, Huihui, Xie, Fuan, Wang, Kaiyu, Wang, Qiang, Huang, Huijuan, Yang, Kunrong, Huang, Suhong, Zhao, Tingting, Wang, Junkai, Chen, Yunyun, Liu, Kuancan, Lan, Xiaopeng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582607/
https://ncbi.nlm.nih.gov/pubmed/31215436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1955-7
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