Development of a novel ssDNA aptamer targeting neutrophil gelatinase-associated lipocalin and its application in clinical trials

BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL) is a promising biomarker of early diagnosis and prediction for acute kidney injury (AKI). However, the current program for NGAL detection is not extensively applied in clinics due to the high expense of antibodies. Nucleic acid aptamers a...

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Foilsithe in:J Transl Med
Main Authors: Hong, Xiaoqian, Yan, Huihui, Xie, Fuan, Wang, Kaiyu, Wang, Qiang, Huang, Huijuan, Yang, Kunrong, Huang, Suhong, Zhao, Tingting, Wang, Junkai, Chen, Yunyun, Liu, Kuancan, Lan, Xiaopeng
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2019
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582607/
https://ncbi.nlm.nih.gov/pubmed/31215436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1955-7
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