Development of a novel ssDNA aptamer targeting neutrophil gelatinase-associated lipocalin and its application in clinical trials

BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL) is a promising biomarker of early diagnosis and prediction for acute kidney injury (AKI). However, the current program for NGAL detection is not extensively applied in clinics due to the high expense of antibodies. Nucleic acid aptamers a...

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Dades bibliogràfiques
Publicat a:J Transl Med
Autors principals: Hong, Xiaoqian, Yan, Huihui, Xie, Fuan, Wang, Kaiyu, Wang, Qiang, Huang, Huijuan, Yang, Kunrong, Huang, Suhong, Zhao, Tingting, Wang, Junkai, Chen, Yunyun, Liu, Kuancan, Lan, Xiaopeng
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582607/
https://ncbi.nlm.nih.gov/pubmed/31215436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1955-7
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