Nortropane alkaloids as pharmacological chaperones in the rescue of equine adipose-derived mesenchymal stromal stem cells affected by metabolic syndrome through mitochondrial potentiation, endoplasmic reticulum stress mitigation and insulin resistance alleviation

OBJECTIVES: Equine metabolic syndrome (EMS) refers to a cluster of associated abnormalities and metabolic disorders, including insulin resistance and adiposity. The numerous biological properties of mesenchymal stem cells (MSCs), including self-renewal and multipotency, have been the subject of many...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Bourebaba, Lynda, Bedjou, Fatiha, Röcken, Michael, Marycz, Krzysztof
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582509/
https://ncbi.nlm.nih.gov/pubmed/31215461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1292-z
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