Inhibition of Protein-Tyrosine Phosphatase PTP1B and LMPTP Promotes Palmitate/Oleate-Challenged HepG2 Cell Survival by Reducing Lipoapoptosis, Improving Mitochondrial Dynamics and Mitigating Oxidative and Endoplasmic Reticulum Stress

Objectives: Non-alcoholic fatty liver disease (NAFLD) is considered a well-known pathology that is determined without using alcohol and has emerged as a growing public health problem. Lipotoxicity is known to promote hepatocyte death, which, in the context of NAFLD, is termed lipoapoptosis. The seve...

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Publicado en:J Clin Med
Autores principales: Bourebaba, Lynda, Łyczko, Jacek, Alicka, Michalina, Bourebaba, Nabila, Szumny, Antoni, Fal, Andrzej M., Marycz, Krzysztof
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7288314/
https://ncbi.nlm.nih.gov/pubmed/32369900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9051294
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