Programmable DNA cleavage by Ago nucleases from mesophilic bacteria Clostridium butyricum and Limnothrix rosea

Argonaute (Ago) proteins are key players in RNA interference in eukaryotes, where they function as RNA-guided RNA endonucleases. Prokaryotic Argonautes (pAgos) are much more diverse than their eukaryotic counterparts but their cellular functions and mechanisms of action remain largely unknown. Some...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Kuzmenko, Anton, Yudin, Denis, Ryazansky, Sergei, Kulbachinskiy, Andrey, Aravin, Alexei A
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Nucleic Acid Enzymes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582412/
https://ncbi.nlm.nih.gov/pubmed/31114878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz379
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