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A programmable pAgo nuclease with universal guide and target specificity from the mesophilic bacterium Kurthia massiliensis

Argonaute proteins are programmable nucleases that are found in both eukaryotes and prokaryotes and provide defense against invading genetic elements. Although some prokaryotic argonautes (pAgos) were shown to recognize RNA targets in vitro, the majority of studied pAgos have strict specificity towa...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Kropocheva, Ekaterina, Kuzmenko, Anton, Aravin, Alexei A, Esyunina, Daria, Kulbachinskiy, Andrey
Format: Artigo
Language:Inglês
Published: Oxford University Press 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053121/
https://ncbi.nlm.nih.gov/pubmed/33744962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab182
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