Accelerated Age-Related Degradation of the Tectorial Membrane in the Ceacam16(βgal/βgal) Null Mutant Mouse, a Model for Late-Onset Human Hereditary Deafness DFNB113

CEACAM16 is a non-collagenous protein of the tectorial membrane, an extracellular structure of the cochlea essential for normal hearing. Dominant and recessive mutations in CEACAM16 have been reported to cause postlingual and progressive forms of deafness in humans. In a previous study of young Ceac...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Goodyear, Richard J., Cheatham, Mary Ann, Naskar, Souvik, Zhou, Yingjie, Osgood, Richard T., Zheng, Jing, Richardson, Guy P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582249/
https://ncbi.nlm.nih.gov/pubmed/31249509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00147
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