Fcmr regulates mononuclear phagocyte control of anti-tumor immunity

Myeloid cells contribute to tumor progression, but how the constellation of receptors they express regulates their functions within the tumor microenvironment (TME) is unclear. We demonstrate that Fcmr (Toso), the putative receptor for soluble IgM, modulates myeloid cell responses to cancer. In a sy...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Kubli, Shawn P., Vornholz, Larsen, Duncan, Gordon, Zhou, Wenjing, Ramachandran, Parameswaran, Fortin, Jerome, Cox, Maureen, Han, SeongJun, Nechanitzky, Robert, Nechanitzky, Duygu, Snow, Bryan E., Jones, Lisa, Li, Wanda Y., Haight, Jillian, Wakeham, Andrew, Bray, Mark R., Mak, Tak W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581943/
https://ncbi.nlm.nih.gov/pubmed/31213601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10619-w
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