Application of cell growth analysis to the quality assessment of human cell-processed therapeutic products as a testing method for immortalized cellular impurities

In human cell-processed therapeutic products (hCTPs) for clinical application, tumorigenic cellular impurities in the manufacturing process are a major concern. Because cellular immortalization is one of the prerequisite steps in tumorigenesis, we tested whether cell growth analysis can be employed...

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Veröffentlicht in:Regen Ther
Hauptverfasser: Hasebe-Takada, Nozomi, Kono, Ken, Yasuda, Satoshi, Sawada, Rumi, Matsuyama, Akifumi, Sato, Yoji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Japanese Society for Regenerative Medicine 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581850/
https://ncbi.nlm.nih.gov/pubmed/31245501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reth.2016.06.005
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