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Positive Feedback Defines the Timing, Magnitude, and Robustness of Angiogenesis

Angiogenesis is driven by the coordinated collective branching of specialized leading “tip” and trailing “stalk” endothelial cells (ECs). While Notch-regulated negative feedback suppresses excessive tip selection, roles for positive feedback in EC identity decisions remain unexplored. Here, by integ...

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Dades bibliogràfiques
Publicat a:Cell Rep
Autors principals: Page, Donna J., Thuret, Raphael, Venkatraman, Lakshmi, Takahashi, Tokiharu, Bentley, Katie, Herbert, Shane P.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581738/
https://ncbi.nlm.nih.gov/pubmed/31189101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.05.052
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