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Tipping the Balance: Robustness of Tip Cell Selection, Migration and Fusion in Angiogenesis

Vascular abnormalities contribute to many diseases such as cancer and diabetic retinopathy. In angiogenesis new blood vessels, headed by a migrating tip cell, sprout from pre-existing vessels in response to signals, e.g., vascular endothelial growth factor (VEGF). Tip cells meet and fuse (anastomosi...

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Detalhes bibliográficos
Main Authors: Bentley, Katie, Mariggi, Giovanni, Gerhardt, Holger, Bates, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762315/
https://ncbi.nlm.nih.gov/pubmed/19876379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000549
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