Antagonistic Glucagon Receptor Antibody Promotes α-Cell Proliferation and Increases β-Cell Mass in Diabetic Mice

Under extreme conditions or by genetic modification, pancreatic α-cells can regenerate and be converted into β-cells. This regeneration holds substantial promise for cell replacement therapy in diabetic patients. The discovery of clinical therapeutic strategies to promote β-cell regeneration is cruc...

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Podrobná bibliografie
Vydáno v:iScience
Hlavní autoři: Wei, Rui, Gu, Liangbiao, Yang, Jin, Yang, Kun, Liu, Junling, Le, Yunyi, Lang, Shan, Wang, Haining, Thai, Dung, Yan, Hai, Hong, Tianpei
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581654/
https://ncbi.nlm.nih.gov/pubmed/31203188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.05.030
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