The lysophosphatidylcholine transporter, MFSD2A, is essential for CD8(+) memory T cell maintenance and secondary response to infection

Access to nutrients is critical for an effective T cell immune response to infection. Although transporters for sugars and amino acids have previously been described in the context of the CD8(+) T cell immune response, the active transport of exogenous fatty acids has remained enigmatic. Here we dis...

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Veröffentlicht in:J Immunol
Hauptverfasser: Piccirillo, Ann R., Hyzny, Eric J., Beppu, Lisa Y., Menk, Ashley V., Wallace, Callen, Hawse, William F., Buechel, Heather M., Wong, Bernice H., Chin Foo, Juat, Cazenave-Gassiot, Amaury, Wenk, Markus R., Delgoffe, Greg M., Watkins, Simon, Silver, David L., D’Cruz, Louise M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581627/
https://ncbi.nlm.nih.gov/pubmed/31127034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801585
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