C13orf31 (FAMIN) is a central regulator of immunometabolic function

Single nucleotide variation in C13orf31 encoding p.C284R and p.I254V in a protein of unknown function causes systemic juvenile idiopathic arthritis, and associates with risk for leprosy and Crohn’s disease, respectively. Here we set out to uncover the underlying mechanism. C13orf31 formed a complex...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Cader, M. Zaeem, Boroviak, Katharina, Zhang, Qifeng, Assadi, Ghazaleh, Kempster, Sarah L., Sewell, Gavin W., Saveljeva, Svetlana, Ashcroft, Jonathan W., Clare, Simon, Mukhopadhyay, Subhankar, Brown, Karen P., Tschurtschenthaler, Markus, Raine, Tim, Doe, Brendan, Chilvers, Edwin R., Griffin, Jules L., Kaneider, Nicole C., Floto, R. Andres, D’Amato, Mauro, Bradley, Allan, Wakelam, Michael J. O., Dougan, Gordon, Kaser, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581540/
https://ncbi.nlm.nih.gov/pubmed/27478939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3532
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