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High levels of cell-free DNA accurately predict late acute kidney injury in patients after cardiac surgery

Use of cardiopulmonary bypass in cardiac surgery triggers systemic inflammation by neutrophil activation leading to neutrophil extracellular traps (NETs) release. Hence, nuclear DNA released by necrotic and apoptotic cells might contribute to an increase in circulating cell-free DNA (cfDNA). cfDNA/N...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Merkle, Julia, Daka, Aldo, Deppe, Antje C., Wahlers, Thorsten, Paunel-Görgülü, Adnana
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581428/
https://ncbi.nlm.nih.gov/pubmed/31211810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218548
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