cfDNA correlates with endothelial damage after cardiac surgery with prolonged cardiopulmonary bypass and amplifies NETosis in an intracellular TLR9-independent manner

Cardiopulmonary bypass (CPB) provokes inflammation culminating in organ dysfunction and increased mortality. Recently, neutrophil extracellular traps (NETs) have been found to be involved in a variety of cardiovascular diseases promoting tissue and organ injury. Here, we aimed to elaborate the proin...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Paunel-Görgülü, Adnana, Wacker, Max, El Aita, Mouhamed, Hassan, Shoreshfan, Schlachtenberger, Georg, Deppe, Antje, Choi, Yeong-Hoon, Kuhn, Elmar, Mehler, Thorsten O., Wahlers, Thorsten
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727170/
https://ncbi.nlm.nih.gov/pubmed/29234042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17561-1
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