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Synthesis of P-enantiomeric deoxyadenosine cyclic 3, 5-phosphorothioates

Treatment of diastereoisomeric mixture of deoxyadenosine-3′- (o-chlorophenyl)-phosphoroanilidates (4) with potassium t-butoxide gave deoxyadenosine cyclic 3′,5′-phosphoroanilidates (5) which were further separated by preparative TLC into P-enantiomeric species. Their stereospecific conversion by mea...

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Publicado en:Nucleic Acids Res
Main Authors: Lesnikowski, Z.J., Stec, W.J., Zielinski, W.S.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 1978
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581408/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/1.suppl_1.s49
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