Awake (18)F-FDG PET Imaging of Memantine-Induced Brain Activation and Test–Retest in Freely Running Mice

PET scans of the mouse brain are usually performed with anesthesia to immobilize the animal. However, it is desirable to avoid the confounding factor of anesthesia in mouse-brain response. Methods: We developed and validated brain PET imaging of awake, freely moving mice. Head-motion tracking was pe...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Miranda, Alan, Glorie, Dorien, Bertoglio, Daniele, Vleugels, Jochen, De Bruyne, Guido, Stroobants, Sigrid, Staelens, Steven, Verhaeghe, Jeroen
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Nuclear Medicine 2019
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581220/
https://ncbi.nlm.nih.gov/pubmed/30442754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.218669
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