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Alzheimer’s Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss in Drosophila

Alzheimer’s disease (AD) is the most common form of dementia and is characterized by intracellular neurofibrillary tangles of hyperphosphorylated Tau, including the 0N4R isoform and accumulation of extracellular amyloid beta (Aβ) plaques. However, less than 5% of AD cases are familial, with many add...

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Detaylı Bibliyografya
Yayımlandı:Front Cell Neurosci
Asıl Yazarlar: Higham, James P., Malik, Bilal R., Buhl, Edgar, Dawson, Jennifer M., Ogier, Anna S., Lunnon, Katie, Hodge, James J. L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581016/
https://ncbi.nlm.nih.gov/pubmed/31244615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00260
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