Hepatitis B Virus Precore Protein p22 Inhibits Alpha Interferon Signaling by Blocking STAT Nuclear Translocation

Antagonism of host immune defenses against hepatitis B virus (HBV) infection by the viral proteins is speculated to cause HBV persistence and the development of chronic hepatitis. The circulating hepatitis B e antigen (HBeAg, p17) is known to manipulate host immune responses to assist in the establi...

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Bibliographic Details
Published in:J Virol
Main Authors: Mitra, Bidisha, Wang, Jinyu, Kim, Elena S., Mao, Richeng, Dong, Minhui, Liu, Yuanjie, Zhang, Jiming, Guo, Haitao
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580977/
https://ncbi.nlm.nih.gov/pubmed/31019054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00196-19
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