Distribution differences in prognostic copy number alteration profiles in IDH-wild-type glioblastoma cause survival discrepancies across cohorts

The diagnosis and prognostication of glioblastoma (GBM) remain to be solely dependent on histopathological findings and few molecular markers, despite the clinical heterogeneity in this entity. To address this issue, we investigated the prognostic impact of copy number alterations (CNAs) using two p...

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Bibliografske podrobnosti
izdano v:Acta Neuropathol Commun
Main Authors: Umehara, Toru, Arita, Hideyuki, Yoshioka, Ema, Shofuda, Tomoko, Kanematsu, Daisuke, Kinoshita, Manabu, Kodama, Yoshinori, Mano, Masayuki, Kagawa, Naoki, Fujimoto, Yasunori, Okita, Yoshiko, Nonaka, Masahiro, Nakajo, Kosuke, Uda, Takehiro, Tsuyuguchi, Naohiro, Fukai, Junya, Fujita, Koji, Sakamoto, Daisuke, Mori, Kanji, Kishima, Haruhiko, Kanemura, Yonehiro
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580599/
https://ncbi.nlm.nih.gov/pubmed/31215469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0749-8
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